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Transient exposure to rotenone causes degeneration and progressive parkinsonian motor deficits, neuroinflammation, and synucleinopathy
Individuals with Parkinson’s disease (PD) typically receive a diagnosis once they have developed motor symptoms, at which point there is already significant loss of substantia nigra dopamine neurons, α-synuclein accumulation in surviving neurons, and neuroinflammation. Consequently, the point of cli...
Autores principales: | Van Laar, Amber D., Webb, Katherine R., Keeney, Matthew T., Van Laar, Victor S., Zharikov, Alevtina, Burton, Edward A., Hastings, Teresa G., Glajch, Kelly E., Hirst, Warren D., Greenamyre, J. Timothy, Rocha, Emily M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421849/ https://www.ncbi.nlm.nih.gov/pubmed/37567894 http://dx.doi.org/10.1038/s41531-023-00561-6 |
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