The role of TLR7 agonists in modulating COVID-19 severity in subjects with loss-of-function TLR7 variants

We investigate the mechanism associated with the severity of COVID-19 in men with TLR7 mutation. Men with loss-of-function (LOF) mutations in TLR7 had severe COVID-19. LOF mutations in TLR7 increased the risk of critical COVID by 16.00-fold (95% confidence interval 2.40–106.73). The deleterious muta...

Descripción completa

Detalles Bibliográficos
Autores principales: Naushad, Shaik Mohammad, Mandadapu, Gowtham, Ramaiah, Mekala Janaki, Almajhdi, Fahad N., Hussain, Tajamul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421879/
https://www.ncbi.nlm.nih.gov/pubmed/37567916
http://dx.doi.org/10.1038/s41598-023-40114-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421879/
https://www.ncbi.nlm.nih.gov/pubmed/37567916
http://dx.doi.org/10.1038/s41598-023-40114-8

Ejemplares similares