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The role of TLR7 agonists in modulating COVID-19 severity in subjects with loss-of-function TLR7 variants
We investigate the mechanism associated with the severity of COVID-19 in men with TLR7 mutation. Men with loss-of-function (LOF) mutations in TLR7 had severe COVID-19. LOF mutations in TLR7 increased the risk of critical COVID by 16.00-fold (95% confidence interval 2.40–106.73). The deleterious muta...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421879/ https://www.ncbi.nlm.nih.gov/pubmed/37567916 http://dx.doi.org/10.1038/s41598-023-40114-8 |