Hydroxyurea and inactivation of checkpoint kinase MEC1 inhibit transcription termination and pre-mRNA cleavage at polyadenylation sites in budding yeast

The DNA damage response (DDR) is an evolutionarily conserved process essential for cell survival. The transcription changes triggered by DDR depend on the nature of DNA damage, activation of checkpoint kinases, and the stage of cell cycle. The transcription changes can be localized and affect only d...

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Detalles Bibliográficos
Autores principales: Kaur, Pritpal, Nagar, Shreya, Mehta, Riddhi, Sahadeo, Kyle, Vancura, Ales
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421882/
https://www.ncbi.nlm.nih.gov/pubmed/37567961
http://dx.doi.org/10.1038/s41598-023-40294-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421882/
https://www.ncbi.nlm.nih.gov/pubmed/37567961
http://dx.doi.org/10.1038/s41598-023-40294-3

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