Spinal cord repair is modulated by the neurogenic factor Hb-egf under direction of a regeneration-associated enhancer

Unlike adult mammals, zebrafish regenerate spinal cord tissue and recover locomotor ability after a paralyzing injury. Here, we find that ependymal cells in zebrafish spinal cords produce the neurogenic factor Hb-egfa upon transection injury. Animals with hb-egfa mutations display defective swim cap...

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Detalles Bibliográficos
Autores principales: Cigliola, Valentina, Shoffner, Adam, Lee, Nutishia, Ou, Jianhong, Gonzalez, Trevor J., Hoque, Jiaul, Becker, Clayton J., Han, Yanchao, Shen, Grace, Faw, Timothy D., Abd-El-Barr, Muhammad M., Varghese, Shyni, Asokan, Aravind, Poss, Kenneth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421883/
https://www.ncbi.nlm.nih.gov/pubmed/37567873
http://dx.doi.org/10.1038/s41467-023-40486-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421883/
https://www.ncbi.nlm.nih.gov/pubmed/37567873
http://dx.doi.org/10.1038/s41467-023-40486-5

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