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Genotyped functional screening of soluble Fab clones enables in-depth analysis of mutation effects
Monoclonal antibodies (mAbs) and their fragments are widely used in therapeutics, diagnostics and basic research. Although display methods such as phage display offer high-throughput, affinities of individual antibodies need to be accurately measured in soluble format. We have developed a screening...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421887/ https://www.ncbi.nlm.nih.gov/pubmed/37567990 http://dx.doi.org/10.1038/s41598-023-40241-2 |