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Photo-dependent cytosolic delivery of shRNA into a single blastomere in a mouse embryo

Single-cell-specific delivery of small RNAs, such as short hairpin RNA (shRNA) and small noncoding RNAs, allows us to elucidate the roles of specific upregulation of RNA expression and RNAi-mediated gene suppression in early embryo development. The photoinduced cytosolic dispersion of RNA (PCDR) met...

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Detalles Bibliográficos
Autores principales: Ikawa, Yuka, Wakai, Takuya, Funahashi, Hiroaki, Soe, Tet Htut, Watanabe, Kazunori, Ohtsuki, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421928/
https://www.ncbi.nlm.nih.gov/pubmed/37567923
http://dx.doi.org/10.1038/s41598-023-40361-9