Domain loss enabled evolution of novel functions in the snake three-finger toxin gene superfamily

Three-finger toxins (3FTXs) are a functionally diverse family of toxins, apparently unique to venoms of caenophidian snakes. Although the ancestral function of 3FTXs is antagonism of nicotinic acetylcholine receptors, redundancy conferred by the accumulation of duplicate genes has facilitated extens...

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Detalles Bibliográficos
Autores principales: Koludarov, Ivan, Senoner, Tobias, Jackson, Timothy N. W., Dashevsky, Daniel, Heinzinger, Michael, Aird, Steven D., Rost, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421932/
https://www.ncbi.nlm.nih.gov/pubmed/37567881
http://dx.doi.org/10.1038/s41467-023-40550-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421932/
https://www.ncbi.nlm.nih.gov/pubmed/37567881
http://dx.doi.org/10.1038/s41467-023-40550-0

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