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Domain loss enabled evolution of novel functions in the snake three-finger toxin gene superfamily
Three-finger toxins (3FTXs) are a functionally diverse family of toxins, apparently unique to venoms of caenophidian snakes. Although the ancestral function of 3FTXs is antagonism of nicotinic acetylcholine receptors, redundancy conferred by the accumulation of duplicate genes has facilitated extens...
Autores principales: | Koludarov, Ivan, Senoner, Tobias, Jackson, Timothy N. W., Dashevsky, Daniel, Heinzinger, Michael, Aird, Steven D., Rost, Burkhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421932/ https://www.ncbi.nlm.nih.gov/pubmed/37567881 http://dx.doi.org/10.1038/s41467-023-40550-0 |
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