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Fluid shear stress enhances natural killer cell's cytotoxicity toward circulating tumor cells through NKG2D-mediated mechanosensing

Tumor cells metastasize to distant organs mainly via hematogenous dissemination, in which circulating tumor cells (CTCs) are relatively vulnerable, and eliminating these cells has great potential to prevent metastasis. In vasculature, natural killer (NK) cells are the major effector lymphocytes for...

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Detalles Bibliográficos
Autores principales: Hu, Bing, Xin, Ying, Hu, Guanshuo, Li, Keming, Tan, Youhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423075/
https://www.ncbi.nlm.nih.gov/pubmed/37575881
http://dx.doi.org/10.1063/5.0156628