Diagnostic applications and therapeutic option of Cascade CRISPR/Cas in the modulation of miRNA in diverse cancers: promises and obstacles

The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas technology is a molecular tool specific to sequences for engineering genomes. Among diverse clusters of Cas proteins, the class 2/type II CRISPR/Cas9 system, despite several challenges, such as off-target effects, editing eff...

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Detalles Bibliográficos
Autores principales: Alinejad, Tahereh, Modarressi, Shabnam, Sadri, Zahra, Hao, Zuo, Chen, Cheng Shui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423114/
https://www.ncbi.nlm.nih.gov/pubmed/37222810
http://dx.doi.org/10.1007/s00432-023-04747-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423114/
https://www.ncbi.nlm.nih.gov/pubmed/37222810
http://dx.doi.org/10.1007/s00432-023-04747-6

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