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Estradiol mitigates stress-induced cardiac injury and inflammation by downregulating ADAM17 via the GPER-1/PI3K signaling pathway

Stress-induced cardiovascular diseases characterized by inflammation are among the leading causes of morbidity and mortality in postmenopausal women worldwide. Estradiol (E2) is known to be cardioprotective via the modulation of inflammatory mediators during stress. But the mechanism is unclear. TNF...

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Detalles Bibliográficos
Autores principales: Adu-Amankwaah, Joseph, Bushi, Aisha, Tan, Rubin, Adekunle, Adebayo Oluwafemi, Adzika, Gabriel Komla, Ndzie Noah, Marie Louise, Nadeem, Iqra, Adzraku, Seyram Yao, Koda, Stephane, Mprah, Richard, Cui, Jie, Li, Kexue, Wowui, Prosperl Ivette, Sun, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423133/
https://www.ncbi.nlm.nih.gov/pubmed/37572114
http://dx.doi.org/10.1007/s00018-023-04886-6