Dual FGFR and VEGFR inhibition synergistically restrain hexokinase 2-dependent lymphangiogenesis and immune escape in intrahepatic cholangiocarcinoma

BACKGROUND: Therapies for cholangiocarcinoma are largely limited and ineffective. Herein, we examined the role of the FGF and VEGF pathways in regulating lymphangiogenesis and PD-L1 expression in intrahepatic cholangiocarcinoma (iCCA). METHODS: The lymphangiogenic functions of FGF and VEGF were eval...

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Detalles Bibliográficos
Autores principales: Peng, Min, Li, Hui, Cao, Huan, Huang, Yamei, Yu, Weiping, Shen, Chuanlai, Gu, Jinyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Original Article―Liver, Pancreas, and Biliary Tract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423168/
https://www.ncbi.nlm.nih.gov/pubmed/37433897
http://dx.doi.org/10.1007/s00535-023-02012-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423168/
https://www.ncbi.nlm.nih.gov/pubmed/37433897
http://dx.doi.org/10.1007/s00535-023-02012-8

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