Modified influenza M1(58–66) peptide vaccination induces non-relevant T-cells and may enhance pathology after challenge

CD8 + T cells are promising targets for vaccination against influenza A virus (IAV) infection. Their induction via peptide vaccination is not trivial, because peptides are weakly immunogenic. One strategy to overcome this is by vaccination with chemically enhanced altered peptide ligands (CPLs), whi...

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Detalles Bibliográficos
Autores principales: Lanfermeijer, Josien, van de Ven, Koen, van Dijken, Harry, Hendriks, Marion, Talavera Ormeño, Cami M. P., de Heij, Femke, Roholl, Paul, Borghans, José A. M., van Baarle, Debbie, de Jonge, Jørgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423225/
https://www.ncbi.nlm.nih.gov/pubmed/37573454
http://dx.doi.org/10.1038/s41541-023-00705-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423225/
https://www.ncbi.nlm.nih.gov/pubmed/37573454
http://dx.doi.org/10.1038/s41541-023-00705-y

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