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Modified influenza M1(58–66) peptide vaccination induces non-relevant T-cells and may enhance pathology after challenge
CD8 + T cells are promising targets for vaccination against influenza A virus (IAV) infection. Their induction via peptide vaccination is not trivial, because peptides are weakly immunogenic. One strategy to overcome this is by vaccination with chemically enhanced altered peptide ligands (CPLs), whi...
Autores principales: | Lanfermeijer, Josien, van de Ven, Koen, van Dijken, Harry, Hendriks, Marion, Talavera Ormeño, Cami M. P., de Heij, Femke, Roholl, Paul, Borghans, José A. M., van Baarle, Debbie, de Jonge, Jørgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423225/ https://www.ncbi.nlm.nih.gov/pubmed/37573454 http://dx.doi.org/10.1038/s41541-023-00705-y |
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