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Glucocorticoid receptor-induced non-muscle caldesmon regulates metastasis in castration-resistant prostate cancer

Lethal prostate cancer (PCa) is characterized by the presence of metastases and development of resistance to therapies. Metastases form in a multi-step process enabled by dynamic cytoskeleton remodeling. An actin cytoskeleton regulating gene, CALD1, encodes a protein caldesmon (CaD). Its isoform, lo...

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Detalles Bibliográficos
Autores principales: Virtanen, Verneri, Paunu, Kreetta, Kukkula, Antti, Niva, Saana, Junila, Ylva, Toriseva, Mervi, Jokilehto, Terhi, Mäkelä, Sari, Huhtaniemi, Riikka, Poutanen, Matti, Paatero, Ilkka, Sundvall, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423232/
https://www.ncbi.nlm.nih.gov/pubmed/37573448
http://dx.doi.org/10.1038/s41389-023-00485-z