Cargando…
Both cell autonomous and non-autonomous processes modulate the association between replication timing and mutation rate
Cancer somatic mutations are the product of multiple mutational and repair processes, some of which are tightly associated with DNA replication. Mutation rates (MR) are known to be higher in late replication timing (RT) regions, but different processes can affect this association. Systematic analysi...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423235/ https://www.ncbi.nlm.nih.gov/pubmed/37573368 http://dx.doi.org/10.1038/s41598-023-39463-1 |