Cargando…
Biosensor Guided Polyketide Synthases Engineering for Optimization of Domain Exchange Boundaries
Type I modular polyketide synthases (PKSs) are multi-domain enzymes functioning like assembly lines. Many engineering attempts have been made for the last three decades to replace, delete and insert new functional domains into PKSs to produce novel molecules. However, inserting heterologous domains...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423236/ https://www.ncbi.nlm.nih.gov/pubmed/37573440 http://dx.doi.org/10.1038/s41467-023-40464-x |