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Infection pre-Ad26.COV2.S-vaccination primes greater class switching and reduced CXCR5 expression by SARS-CoV-2-specific memory B cells

Neutralizing antibodies strongly correlate with protection for COVID-19 vaccines, but the corresponding memory B cells that form to protect against future infection are relatively understudied. Here we examine the effect of prior SARS-CoV-2 infection on the magnitude and phenotype of the memory B ce...

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Detalles Bibliográficos
Autores principales: Krause, Robert G. E., Moyo-Gwete, Thandeka, Richardson, Simone I., Makhado, Zanele, Manamela, Nelia P., Hermanus, Tandile, Mkhize, Nonhlanhla N., Keeton, Roanne, Benede, Ntombi, Mennen, Mathilda, Skelem, Sango, Karim, Farina, Khan, Khadija, Riou, Catherine, Ntusi, Ntobeko A. B., Goga, Ameena, Gray, Glenda, Hanekom, Willem, Garrett, Nigel, Bekker, Linda-Gail, Groll, Andreas, Sigal, Alex, Moore, Penny L., Burgers, Wendy A., Leslie, Alasdair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423246/
https://www.ncbi.nlm.nih.gov/pubmed/37573434
http://dx.doi.org/10.1038/s41541-023-00724-9