The APC/C E3 ligase subunit ANAPC11 mediates FOXO3 protein degradation to promote cell proliferation and lymph node metastasis in urothelial bladder cancer

Urothelial bladder cancer (UBC) is one of the most prevalent malignancies worldwide, with striking tumor heterogeneity. Elucidating the molecular mechanisms that can be exploited for the treatment of aggressive UBC is a particularly relevant goal. Protein ubiquitination is a critical post-translatio...

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Detalles Bibliográficos
Autores principales: Yan, Dong, He, Qingqing, Pei, Lu, Yang, Meihua, Huang, Lifang, Kong, Jianqiu, He, Wang, Liu, Hao, Xu, Shizhong, Qin, Haide, Lin, Tianxin, Huang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423259/
https://www.ncbi.nlm.nih.gov/pubmed/37573356
http://dx.doi.org/10.1038/s41419-023-06000-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423259/
https://www.ncbi.nlm.nih.gov/pubmed/37573356
http://dx.doi.org/10.1038/s41419-023-06000-x

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