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IF1 promotes oligomeric assemblies of sluggish ATP synthase and outlines the heterogeneity of the mitochondrial membrane potential

The coexistence of two pools of ATP synthase in mitochondria has been largely neglected despite in vitro indications for the existence of reversible active/inactive state transitions in the F1-domain of the enzyme. Herein, using cells and mitochondria from mouse tissues, we demonstrate the existence...

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Detalles Bibliográficos
Autores principales: Romero-Carramiñana, Inés, Esparza-Moltó, Pau B., Domínguez-Zorita, Sonia, Nuevo-Tapioles, Cristina, Cuezva, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423274/
https://www.ncbi.nlm.nih.gov/pubmed/37573449
http://dx.doi.org/10.1038/s42003-023-05214-1