Profiling of the genetic features of Chinese patients with gastric cancer with HRD germline mutations in a large-scale retrospective study

BACKGROUND: Approximately 10% of gastric cancers (GCs) are associated with strong familial clustering and can be attributed to genetic predisposition. Homologous recombination deficiency (HRD) leads to genomic instability and accumulation of genetic variations, playing an important role in the devel...

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Detalles Bibliográficos
Autores principales: Zhang, Chenghai, Zhu, Dandan, Qu, Yurong, Shi, Min, Ma, Jingjiao, Peng, Yebo, Zhu, Bowen, Tao, Houquan, Ma, Tonghui, Hou, TieYing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Cancer Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423538/
https://www.ncbi.nlm.nih.gov/pubmed/36627197
http://dx.doi.org/10.1136/jmg-2022-108816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423538/
https://www.ncbi.nlm.nih.gov/pubmed/36627197
http://dx.doi.org/10.1136/jmg-2022-108816

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