Neoadjuvant use of oncolytic herpes virus G47Δ prevents local recurrence after insufficient resection in tongue cancer models

A complete resection of tongue cancer is often difficult. We investigate the usefulness of administering G47Δ (teserpaturev), a triple-mutated oncolytic herpes simplex virus type 1, prior to resection. G47Δ exhibits good cytopathic effects and replication capabilities in all head and neck cancer cel...

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Detalles Bibliográficos
Autores principales: Inoue, Kosuke, Ito, Hirotaka, Iwai, Miwako, Tanaka, Minoru, Mori, Yoshiyuki, Todo, Tomoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423690/
https://www.ncbi.nlm.nih.gov/pubmed/37583387
http://dx.doi.org/10.1016/j.omto.2023.07.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423690/
https://www.ncbi.nlm.nih.gov/pubmed/37583387
http://dx.doi.org/10.1016/j.omto.2023.07.002

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