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Circadian regulator CLOCK promotes tumor angiogenesis in glioblastoma

Glioblastoma (GBM) is one of the most aggressive tumors in the adult central nervous system. We previously revealed that circadian regulation of glioma stem cells (GSCs) affects GBM hallmarks of immunosuppression and GSC maintenance in a paracrine and autocrine manner. Here, we expand the mechanism...

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Detalles Bibliográficos
Autores principales: Pang, Lizhi, Dunterman, Madeline, Xuan, Wenjing, Gonzalez, Annette, Lin, Yiyun, Hsu, Wen-Hao, Khan, Fatima, Hagan, Robert S., Muller, William A., Heimberger, Amy B., Chen, Peiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423747/
https://www.ncbi.nlm.nih.gov/pubmed/36795563
http://dx.doi.org/10.1016/j.celrep.2023.112127