Single-nucleus RNA sequencing in ischemic cardiomyopathy reveals common transcriptional profile underlying end-stage heart failure

Simonson et al. compare non-failing and ischemic cardiomyopathy human left ventricles using snRNA-seq and identify an increase in lymphatic and angiogenic endothelial cells in disease. Transcriptionally, ischemic cardiomyopathy is similar to other cardiomyopathies. Gene targets from this shared expr...

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Detalles Bibliográficos
Autores principales: Simonson, Bridget, Chaffin, Mark, Hill, Matthew C., Atwa, Ondine, Guedira, Yasmine, Bhasin, Harshit, Hall, Amelia W., Hayat, Sikander, Baumgart, Simon, Bedi, Kenneth C., Margulies, Kenneth B., Klattenhoff, Carla A., Ellinor, Patrick T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423750/
https://www.ncbi.nlm.nih.gov/pubmed/36790929
http://dx.doi.org/10.1016/j.celrep.2023.112086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423750/
https://www.ncbi.nlm.nih.gov/pubmed/36790929
http://dx.doi.org/10.1016/j.celrep.2023.112086

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