Oncolytic virus-driven immune remodeling revealed in mouse medulloblastomas at single cell resolution

Oncolytic viruses, modified for tumor-restricted infection, are a promising cancer immunotherapeutic, yet much remains to be understood about factors driving their activity and outcome in the tumor microenvironment. Here, we report that oncolytic herpes simplex virus C134, previously found to exert...

Descripción completa

Detalles Bibliográficos
Autores principales: Hedberg, Jack, Studebaker, Adam, Smith, Luke, Chen, Chun-Yu, Westfall, Jesse J., Cam, Maren, Gross, Amy, Hernandez-Aguirre, Ilse, Martin, Alexia, Kim, Doyeon, Dhital, Ravi, Kim, Yeaseul, Roberts, Ryan D., Cripe, Timothy P., Mardis, Elaine R., Cassady, Kevin A., Leonard, Jeffrey, Miller, Katherine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424001/
https://www.ncbi.nlm.nih.gov/pubmed/37583388
http://dx.doi.org/10.1016/j.omto.2023.07.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424001/
https://www.ncbi.nlm.nih.gov/pubmed/37583388
http://dx.doi.org/10.1016/j.omto.2023.07.006

Ejemplares similares