CuI-catalyzed synthesis of multisubstituted pyrido[1,2-a]pyrimidin-4-ones through tandem Ullmann-type C–N cross-coupling and intramolecular amidation reaction

Various multi-substituted pyrido[1,2-a]pyrimidin-4-ones were synthesized via a one-pot tandem CuI-catalyzed C–N bond formation/intramolecular amidation reaction at 130 °C in DMF. This protocol features simple operation, broad substrate scope, good functional group tolerance and gram scale preparatio...

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Detalles Bibliográficos
Autores principales: Mo, Baichuan, Chen, Chunxia, Peng, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424054/
https://www.ncbi.nlm.nih.gov/pubmed/37583662
http://dx.doi.org/10.1039/d3ra04454h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424054/
https://www.ncbi.nlm.nih.gov/pubmed/37583662
http://dx.doi.org/10.1039/d3ra04454h

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