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Ex vivo and In vitro antiplasmodial activities of approved drugs predicted to have antimalarial activities using chemogenomics and drug repositioning approach

High malaria mortality coupled with increased emergence of resistant multi-drug resistant strains of Plasmodium parasite, warrants the development of new and effective antimalarial drugs. However, drug design and discovery are costly and time-consuming with many active antimalarial compounds failing...

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Detalles Bibliográficos
Autores principales: Ochora, Douglas O., Mogire, Reagan M., Masai, Rael J., Yeda, Redemptah A., Mwakio, Edwin W., Amwoma, Joseph G., Wakoli, Dancan M., Yenesew, Abiy, Akala, Hoseah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424068/
https://www.ncbi.nlm.nih.gov/pubmed/37583763
http://dx.doi.org/10.1016/j.heliyon.2023.e18863