Porcine reproductive and respiratory syndrome virus upregulates SMPDL3B to promote viral replication by modulating lipid metabolism

Porcine reproductive and respiratory syndrome virus (PRRSV) poses a severe threat to the health of pigs globally. Host factors play a critical role in PRRSV replication. Using PRRSV as a model for genome-scale CRISPR knockout (KO) screening, we identified a host factor critical to PRRSV infection: s...

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Detalles Bibliográficos
Autores principales: Shen, Huan-Huan, Zhao, Qin, Wen, Yi-Ping, Wu, Rui, Du, Sen-Yan, Huang, Xiao-Bo, Wen, Xin-Tian, Cao, San-Jie, Zeng, Lei, Yan, Qi-Gui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424083/
https://www.ncbi.nlm.nih.gov/pubmed/37583552
http://dx.doi.org/10.1016/j.isci.2023.107450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424083/
https://www.ncbi.nlm.nih.gov/pubmed/37583552
http://dx.doi.org/10.1016/j.isci.2023.107450

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