Cargando…

Individual phosphatidylinositol transfer proteins have distinct functions that do not involve lipid transfer activity

Platelets use signal transduction pathways facilitated by class I phosphatidylinositol transfer proteins (PITPs). The 2 mammalian class I PITPs, PITPα and PITPβ, are single PITP domain soluble proteins that are encoded by different genes and share 77% sequence identity, although their individual rol...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Liang, Thorsheim, Chelsea L., Suzuki, Aae, Stalker, Timothy J., Min, Sang H., Krishnaswamy, Sriram, Cockcroft, Shamshad, Anderson, Karen E., Weiderhold, Brittany, Abrams, Charles S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424146/
https://www.ncbi.nlm.nih.gov/pubmed/36930803
http://dx.doi.org/10.1182/bloodadvances.2022008735