Cargando…
Telomerase-targeted therapies in myeloid malignancies
Human telomeres are tandem arrays that are predominantly composed of 5′-TTAGGG-3′ nucleotide sequences at the terminal ends of chromosomes. These sequences serve 2 primary functions: they preserve genomic integrity by protecting the ends of chromosomes, preventing inappropriate degradation by DNA re...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Hematology
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424149/ https://www.ncbi.nlm.nih.gov/pubmed/37216228 http://dx.doi.org/10.1182/bloodadvances.2023009903 |