TRAF7 is an essential regulator of blood vessel integrity during mouse embryonic and neonatal development

Targeted deletion of TRAF7 revealed that it is a crucial part of shear stress-responsive MEKK3-MEK5-ERK5 signaling pathway induced in endothelial cells by blood flow. Similar to Mekk3-, Mek5- or Erk5-deficient mice, Traf7-deficient embryos died in utero around midgestation due to impaired endotheliu...

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Detalles Bibliográficos
Autores principales: Tsitsikov, Erdyni N., Phan, Khanh P., Liu, Yufeng, Tsytsykova, Alla V., Kinter, Mike, Selland, Lauren, Garman, Lori, Griffin, Courtney, Dunn, Ian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424150/
https://www.ncbi.nlm.nih.gov/pubmed/37583551
http://dx.doi.org/10.1016/j.isci.2023.107474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424150/
https://www.ncbi.nlm.nih.gov/pubmed/37583551
http://dx.doi.org/10.1016/j.isci.2023.107474

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