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Disrupting Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) Latent Replication with a Small Molecule Inhibitor

[Image: see text] Kaposi’s sarcoma-associated herpesvirus (KSHV) can establish latent lifelong infections in infected individuals. During viral latency, the latency-associated nuclear antigen (LANA) mediates the replication of the latent viral genome in dividing cells and tethers them to mitotic chr...

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Detalles Bibliográficos
Autores principales: Berwanger, Aylin, Stein, Saskia C., Kany, Andreas M., Gartner, Melissa, Loretz, Brigitta, Lehr, Claus-Michael, Hirsch, Anna K. H., Schulz, Thomas F., Empting, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424179/
https://www.ncbi.nlm.nih.gov/pubmed/37506283
http://dx.doi.org/10.1021/acs.jmedchem.3c00990