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Deubiquitinase USP9X stabilizes RNA m(6)A demethylase ALKBH5 and promotes acute myeloid leukemia cell survival
Post-translational modifications including protein ubiquitination regulate a plethora of cellular processes in distinct manners. RNA N(6)-methyladenosine is the most abundant post-transcriptional modification on mammalian mRNAs and plays important roles in various physiological and pathological cond...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424212/ https://www.ncbi.nlm.nih.gov/pubmed/37454738 http://dx.doi.org/10.1016/j.jbc.2023.105055 |