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Deubiquitinase USP9X stabilizes RNA m(6)A demethylase ALKBH5 and promotes acute myeloid leukemia cell survival

Post-translational modifications including protein ubiquitination regulate a plethora of cellular processes in distinct manners. RNA N(6)-methyladenosine is the most abundant post-transcriptional modification on mammalian mRNAs and plays important roles in various physiological and pathological cond...

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Detalles Bibliográficos
Autores principales: Wang, Peipei, Wang, Jing, Yao, Shuxin, Cui, Manman, Cheng, Ying, Liu, Weidong, Gao, Zhuying, Hu, Jin, Zhang, Jinfang, Zhang, Haojian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424212/
https://www.ncbi.nlm.nih.gov/pubmed/37454738
http://dx.doi.org/10.1016/j.jbc.2023.105055