Ionizable Amino Lipids Distribution and Effects on DSPC/Cholesterol Membranes: Implications for Lipid Nanoparticle Structure

[Image: see text] Lipid nanoparticles (LNPs) containing ionizable aminolipids are among the leading platforms for the successful delivery of nucleic-acid-based therapeutics, including messenger RNA (mRNA). The two recently FDA-approved COVID-19 vaccines developed by Moderna and Pfizer/BioNTech belon...

Descripción completa

Detalles Bibliográficos
Autores principales: Dehghani-Ghahnaviyeh, Sepehr, Smith, Michael, Xia, Yan, Dousis, Athanasios, Grossfield, Alan, Sur, Sreyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424244/
https://www.ncbi.nlm.nih.gov/pubmed/37498794
http://dx.doi.org/10.1021/acs.jpcb.3c01296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424244/
https://www.ncbi.nlm.nih.gov/pubmed/37498794
http://dx.doi.org/10.1021/acs.jpcb.3c01296

Ejemplares similares