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Ionizable Amino Lipids Distribution and Effects on DSPC/Cholesterol Membranes: Implications for Lipid Nanoparticle Structure

[Image: see text] Lipid nanoparticles (LNPs) containing ionizable aminolipids are among the leading platforms for the successful delivery of nucleic-acid-based therapeutics, including messenger RNA (mRNA). The two recently FDA-approved COVID-19 vaccines developed by Moderna and Pfizer/BioNTech belon...

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Detalles Bibliográficos
Autores principales:	Dehghani-Ghahnaviyeh, Sepehr, Smith, Michael, Xia, Yan, Dousis, Athanasios, Grossfield, Alan, Sur, Sreyoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424244/ https://www.ncbi.nlm.nih.gov/pubmed/37498794 http://dx.doi.org/10.1021/acs.jpcb.3c01296

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