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Therapeutic potential of melatonin in the intervertebral disc degeneration through inhibiting the ferroptosis of nucleus pulpous cells

Ferroptosis, a novel type of cell death mediated by the iron‐dependent lipid peroxidation, contributes to the pathogenesis of the intervertebral disc degeneration (IDD). Increasing evidence demonstrated that melatonin (MLT) displayed the therapeutic potential to prevent the development of IDD. Curre...

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Detalles Bibliográficos
Autores principales: Dou, Xinyu, Ma, Yunlong, Luo, Qipeng, Song, Chunyu, Liu, Meijuan, Liu, Xiao, Jia, Donglin, Li, Shuiqing, Liu, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424295/
https://www.ncbi.nlm.nih.gov/pubmed/37329158
http://dx.doi.org/10.1111/jcmm.17818