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Synthesis and Evaluation of Bithiazole Derivatives As Potential α-Sarcoglycan Correctors

[Image: see text] 4′-Methyl-4,5′-bithiazoles were previously identified as cystic fibrosis transmembrane regulator (CFTR) correctors, thus being able to correct folding defective mutants of the channel regulating chloride transport through the membrane. Additionally, bithiazole derivative C17 was re...

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Detalles Bibliográficos
Autores principales: Ribaudo, Giovanni, Carotti, Marcello, Ongaro, Alberto, Oselladore, Erika, Scano, Martina, Zagotto, Giuseppe, Sandonà, Dorianna, Gianoncelli, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424318/
https://www.ncbi.nlm.nih.gov/pubmed/37583821
http://dx.doi.org/10.1021/acsmedchemlett.3c00046