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Synthesis and Evaluation of Bithiazole Derivatives As Potential α-Sarcoglycan Correctors
[Image: see text] 4′-Methyl-4,5′-bithiazoles were previously identified as cystic fibrosis transmembrane regulator (CFTR) correctors, thus being able to correct folding defective mutants of the channel regulating chloride transport through the membrane. Additionally, bithiazole derivative C17 was re...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424318/ https://www.ncbi.nlm.nih.gov/pubmed/37583821 http://dx.doi.org/10.1021/acsmedchemlett.3c00046 |