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CRISPR-Cas9 identifies growth-related subtypes of glioblastoma with therapeutical significance through cell line knockdown

BACKGROUND: Glioblastoma (GBM) is a type of highly malignant brain tumor that is known for its significant intratumoral heterogeneity, meaning that there can be a high degree of variability within the tumor tissue. Despite the identification of several subtypes of GBM in recent years, there remains...

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Detalles Bibliográficos
Autores principales: Zhao, Nannan, Weng, Siyuan, Liu, Zaoqu, Xu, Hui, Ren, Yuqin, Guo, Chunguang, Liu, Long, Zhang, Zhenyu, Ji, Yuchen, Han, Xinwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424363/
https://www.ncbi.nlm.nih.gov/pubmed/37580710
http://dx.doi.org/10.1186/s12885-023-11131-7