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Impact of mixing insufficiencies on L-phenylalanine production with an Escherichia coli reporter strain in a novel two-compartment bioreactor

BACKGROUND: The omnipresence of population heterogeneity in industrial bioprocesses originates from prevailing dynamic bioprocess conditions, which promote differences in the expression of cellular characteristics. Despite the awareness, the concrete consequences of this phenomenon remain poorly und...

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Detalles Bibliográficos
Autores principales: Hoang, Manh Dat, Polte, Ingmar, Frantzmann, Lukas, von den Eichen, Nikolas, Heins, Anna-Lena, Weuster-Botz, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424407/
https://www.ncbi.nlm.nih.gov/pubmed/37574555
http://dx.doi.org/10.1186/s12934-023-02165-4