Macrophage targeted polymeric curcumin nanoparticles limit intracellular survival of Mycobacterium tuberculosis through induction of autophagy and augment anti-TB activity of isoniazid in RAW 264.7 macrophages

Rapid emergence of antibiotic resistance in tuberculosis has left us with limited resources to treat and manage multi drug resistant (MDR) cases of tuberculosis, prompting the development of novel therapeutics. Mycobacterium tuberculosis (MTB) perturbs the host protective pathways for its survival,...

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Detalles Bibliográficos
Autores principales: Gupta, Pramod Kumar, Jahagirdar, Priyanka, Tripathi, Devavrat, Devarajan, Padma V., Kulkarni, Savita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424441/
https://www.ncbi.nlm.nih.gov/pubmed/37583694
http://dx.doi.org/10.3389/fimmu.2023.1233630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424441/
https://www.ncbi.nlm.nih.gov/pubmed/37583694
http://dx.doi.org/10.3389/fimmu.2023.1233630

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