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B cell receptor signaling in germinal centers prolongs survival and primes B cells for selection

Germinal centers (GCs) are sites of B cell clonal expansion, diversification, and antibody affinity selection. This process is limited and directed by T follicular helper cells that provide helper signals to B cells that endocytose, process, and present cognate antigens in proportion to their B cell...

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Detalles Bibliográficos
Autores principales: Chen, Spencer T., Oliveira, Thiago Y., Gazumyan, Anna, Cipolla, Melissa, Nussenzweig, Michel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424567/
https://www.ncbi.nlm.nih.gov/pubmed/36882061
http://dx.doi.org/10.1016/j.immuni.2023.02.003