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B cell receptor signaling in germinal centers prolongs survival and primes B cells for selection
Germinal centers (GCs) are sites of B cell clonal expansion, diversification, and antibody affinity selection. This process is limited and directed by T follicular helper cells that provide helper signals to B cells that endocytose, process, and present cognate antigens in proportion to their B cell...
Autores principales: | Chen, Spencer T., Oliveira, Thiago Y., Gazumyan, Anna, Cipolla, Melissa, Nussenzweig, Michel C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424567/ https://www.ncbi.nlm.nih.gov/pubmed/36882061 http://dx.doi.org/10.1016/j.immuni.2023.02.003 |
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