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5hmC Immunohistochemistry: A Predictor of TERT Promoter Mutational Status in Follicular Thyroid Carcinoma?

Telomerase reverse transcriptase (TERT) gene aberrancies correlate to adverse prognosis in follicular thyroid carcinoma (FTC). As loss of 5-hydroxymethylcytosine (5hmC) has been associated with TERT promoter mutations in papillary thyroid carcinoma, this study sought to analyze the levels of 5hmC in...

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Detalles Bibliográficos
Autores principales: Hysek, Martin, Hellgren, Samuel L., Condello, Vincenzo, Xu, Yiyi, Larsson, Catharina, Zedenius, Jan, Juhlin, C. Christofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424576/
https://www.ncbi.nlm.nih.gov/pubmed/37486076
http://dx.doi.org/10.1369/00221554231190437