ZNF143 inhibits hepatocyte mitophagy and promotes non-alcoholic fatty liver disease by targeting increased lncRNA NEAT1 expression to activate ROCK2 pathway

Background: Nonalcoholic fatty liver disease (NAFLD) is the most common hepatic disorders worldwide. The mitophagy is suggested to be repressed in NAFLD, but the mechanism remains to be elucidated. Methods: NAFLD cell and mouse models were established by treating with free fatty acid (FFA) and feedi...

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Detalles Bibliográficos
Autores principales: Dong, Yujie, Hu, Minjie, Tan, Kewei, Dai, Rongjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424604/
https://www.ncbi.nlm.nih.gov/pubmed/37566742
http://dx.doi.org/10.1080/15592294.2023.2239592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424604/
https://www.ncbi.nlm.nih.gov/pubmed/37566742
http://dx.doi.org/10.1080/15592294.2023.2239592

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