IL-6 and IL-27 play both distinct and redundant roles in regulating CD4 T-cell responses during chronic viral infection

The IL-6 cytokine family signals through the common signal transduction molecule gp130 combined with a cytokine-specific receptor. Gp130 signaling on CD4 T cells is vital in controlling chronic infection of mice with lymphocytic choriomeningitis virus clone 13 (LCMV Cl13), but the precise role of in...

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Detalles Bibliográficos
Autores principales: Harker, James A., Greene, Trever T., Barnett, Burton E., Bao, Phuc, Dolgoter, Aleksandr, Zuniga, Elina I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424726/
https://www.ncbi.nlm.nih.gov/pubmed/37583704
http://dx.doi.org/10.3389/fimmu.2023.1221562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424726/
https://www.ncbi.nlm.nih.gov/pubmed/37583704
http://dx.doi.org/10.3389/fimmu.2023.1221562

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