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Thermus thermophilus Argonaute-based signal amplifier for highly sensitive and specific microRNA detection

The prokaryote-derived gene defense system as a new generation of nucleic acid detection tool exhibits impressive performance in the field of molecular diagnosis. Prokaryotic Argonaute (Ago) is a CRISPR-associated protein that is guided by a short DNA (gDNA) and then efficiently cleaves gDNA-complem...

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Detalles Bibliográficos
Autores principales: Wang, Ziqi, Wang, Zitong, Zhang, Fan, Wu, Lingyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424790/
https://www.ncbi.nlm.nih.gov/pubmed/37583711
http://dx.doi.org/10.3389/fbioe.2023.1221943