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PERK Inhibition Suppresses Neovascularization and Protects Neurons During Ischemia-Induced Retinopathy

PURPOSE: Retinal ischemia is a common cause of a variety of eye diseases, such as retinopathy of prematurity, diabetic retinopathy, and vein occlusion. Protein kinase RNA-activated-like endoplasmic reticulum (ER) kinase (PERK), one of the main ER stress sensor proteins, has been involved in many dis...

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Detalles Bibliográficos
Autores principales: Shi, Shuizhen, Ding, Chun, Zhu, Shuang, Xia, Fan, Buscho, Seth E., Li, Shengguo, Motamedi, Massoud, Liu, Hua, Zhang, Wenbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424802/
https://www.ncbi.nlm.nih.gov/pubmed/37566408
http://dx.doi.org/10.1167/iovs.64.11.17