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Synthesis of 1,2,3-triazoles using Grignard reactions through the protection of azides

An efficient method to prepare organomagnesium intermediates having a protected azido group is reported. Protection of azido groups with di-(tert-butyl)(4-(dimethylamino)phenylphosphine (amphos) and following iodine–magnesium exchange realized the preparation of organomagnesium intermediates, which...

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Detalles Bibliográficos
Autores principales: Namioka, Rina, Suzuki, Minori, Yoshida, Suguru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424848/
https://www.ncbi.nlm.nih.gov/pubmed/37583567
http://dx.doi.org/10.3389/fchem.2023.1237878